{"id":2555,"date":"2021-02-02T19:59:54","date_gmt":"2021-02-02T19:59:54","guid":{"rendered":"https:\/\/lightox.co.uk\/?p=2555"},"modified":"2021-12-07T06:10:49","modified_gmt":"2021-12-07T06:10:49","slug":"lighting-the-way-out-of-skin-fibrosis","status":"publish","type":"post","link":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/","title":{"rendered":"Lighting the Way Out of Skin Fibrosis"},"content":{"rendered":"<div class=\"wpb-content-wrapper\">[vc_row][vc_column]\t<div id=\"thb-image-67370694aaa27\" class=\"caption-style1  aligncenter   thb_image_link wp-caption \">\n\t\t\t<div class=\"thb-image-inner size_100\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2000\" height=\"1415\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" class=\"thb_image retina_size   attachment-full thb-lazyload lazyload\" alt=\"\" title=\"APOLLO_Logo_2000px\" sizes=\"(max-width: 2000px) 100vw, 2000px\" data-src=\"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px.jpg\" data-sizes=\"auto\" data-srcset=\"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px.jpg 2000w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-300x212.jpg 300w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-1024x724.jpg 1024w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-150x106.jpg 150w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-768x543.jpg 768w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-1536x1087.jpg 1536w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-380x269.jpg 380w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-20x14.jpg 20w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-190x134.jpg 190w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-760x538.jpg 760w, https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO_Logo_2000px-1140x807.jpg 1140w\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t[vc_row_inner][vc_column_inner][vc_column_text]\n<h5>LightOx are delighted to announce that we have joined forces with Radboud University Medical Center (Radboud UMC) and Dr. Marije Koenders and her group to begin project \u201cAPOLLO\u201d.<\/h5>\n[\/vc_column_text][vc_column_text]Together this project will seek to establish an anti-fibrotic phototherapy for the treatment of patients with scleroderma. Scleroderma is an autoimmune disease that is characterised by an uncontrolled production of collagen that leads to pronounced skin and tissue thickening. This skin thickening often has a detrimental effect on patient\u2019s quality of life, and can cause difficulties with movement, cardiovascular issues and digestive problems among many other symptoms.<\/p>\n<p>Scleroderma affects around 180,000 people in Europe, and there is currently no effective treatment for those with the disease.<\/p>\n<p>Dr. Koenders\u2019 team have recently developed a revolutionary strategy to eliminate pathogenic skin fibroblasts implicated in the onset of scleroderma by attaching light-activated drugs to targeting antibodies, enabling highly specific destruction of these problematic cells.<\/p>\n<p>Project APOLLO will bring together the teams at LightOx and Radboud UMC to couple our next-generation photosensitisers to these targeting antibodies, and apply them using in-vivo models to ascertain their utility in the fight against scleroderma with a view to progress these novel antibody conjugates towards the clinic.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner css=&#8221;.vc_custom_1585214140354{padding-top: 3vh !important;}&#8221;][vc_column_inner el_class=&#8221;text-center&#8221;]\t<a id=\"thb-button-67370694ab058\" class=\"btn style1 large  gradient pill-radius animation bottom-to-top   \" href=\"http:\/\/www.radboudumc.nl\" target=\"_blank\" role=\"button\">\n\t\t<span>Radboudumc<\/span>\n\t\t\t<\/a>\n\t\t\t<style>\n\n\t\t\t\t\t\t\t\t\/* Style1 *\/\n\t\t\t\t#thb-button-67370694ab058.style1 {\n\t\t\t\t\tbackground:#1e73be;background:linear-gradient( -135deg,#1e73be,#1e73be );\t\t\t\t}\n\t\t\t\t#thb-button-67370694ab058.style1:after {\n\t\t\t\t\tbackground: #1e73be;\n\t\t\t\t}\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/style>\n\t\t[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_column_text] LightOx are delighted to announce that we have joined forces with Radboud University Medical Center (Radboud UMC) and Dr. Marije Koenders and her group to begin project \u201cAPOLLO\u201d. [\/vc_column_text][vc_column_text]Together this project will seek to establish an anti-fibrotic phototherapy for the treatment of patients with scleroderma. Scleroderma is an autoimmune disease that is characterised by&hellip;<\/p>\n","protected":false},"author":3,"featured_media":2562,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[6],"tags":[8],"class_list":["post-2555","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-collaboration","tag-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Lighting the Way Out of Skin Fibrosis - LIGHTOX<\/title>\n<meta name=\"description\" content=\"LightOx are delighted to announce that we have joined forces with Dr. Marije Koenders and her group at Radboud University Medical Center.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lighting the Way Out of Skin Fibrosis - LIGHTOX\" \/>\n<meta property=\"og:description\" content=\"LightOx are delighted to announce that we have joined forces with Dr. Marije Koenders and her group at Radboud University Medical Center.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/\" \/>\n<meta property=\"og:site_name\" content=\"LIGHTOX\" \/>\n<meta property=\"article:published_time\" content=\"2021-02-02T19:59:54+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-12-07T06:10:49+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"707\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"LIGHTOX TEAM\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@lightox5\" \/>\n<meta name=\"twitter:site\" content=\"@lightox5\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"LIGHTOX TEAM\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/\"},\"author\":{\"name\":\"LIGHTOX TEAM\",\"@id\":\"https:\/\/lightox.co.uk\/#\/schema\/person\/1c4c5240ed66920f7bf1ad0e3cd4034f\"},\"headline\":\"Lighting the Way Out of Skin Fibrosis\",\"datePublished\":\"2021-02-02T19:59:54+00:00\",\"dateModified\":\"2021-12-07T06:10:49+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/\"},\"wordCount\":306,\"publisher\":{\"@id\":\"https:\/\/lightox.co.uk\/#organization\"},\"image\":{\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg\",\"keywords\":[\"News\"],\"articleSection\":[\"Collaboration\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/\",\"url\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/\",\"name\":\"Lighting the Way Out of Skin Fibrosis - LIGHTOX\",\"isPartOf\":{\"@id\":\"https:\/\/lightox.co.uk\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg\",\"datePublished\":\"2021-02-02T19:59:54+00:00\",\"dateModified\":\"2021-12-07T06:10:49+00:00\",\"description\":\"LightOx are delighted to announce that we have joined forces with Dr. Marije Koenders and her group at Radboud University Medical Center.\",\"breadcrumb\":{\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#primaryimage\",\"url\":\"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg\",\"contentUrl\":\"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg\",\"width\":1000,\"height\":707},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/lightox.co.uk\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Lighting the Way Out of Skin Fibrosis\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/lightox.co.uk\/#website\",\"url\":\"https:\/\/lightox.co.uk\/\",\"name\":\"LIGHTOX\",\"description\":\"illuminating therapeutics &amp; research tools\",\"publisher\":{\"@id\":\"https:\/\/lightox.co.uk\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/lightox.co.uk\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/lightox.co.uk\/#organization\",\"name\":\"LightOx Limited\",\"url\":\"https:\/\/lightox.co.uk\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/lightox.co.uk\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"LightOx Limited\"},\"image\":{\"@id\":\"https:\/\/lightox.co.uk\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/x.com\/lightox5\",\"https:\/\/www.linkedin.com\/company\/lightox-limited\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/lightox.co.uk\/#\/schema\/person\/1c4c5240ed66920f7bf1ad0e3cd4034f\",\"name\":\"LIGHTOX TEAM\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/lightox.co.uk\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/b2ad47e1a5396b65810aa5710c6ebf4b?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/b2ad47e1a5396b65810aa5710c6ebf4b?s=96&d=mm&r=g\",\"caption\":\"LIGHTOX TEAM\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Lighting the Way Out of Skin Fibrosis - LIGHTOX","description":"LightOx are delighted to announce that we have joined forces with Dr. Marije Koenders and her group at Radboud University Medical Center.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/","og_locale":"en_US","og_type":"article","og_title":"Lighting the Way Out of Skin Fibrosis - LIGHTOX","og_description":"LightOx are delighted to announce that we have joined forces with Dr. Marije Koenders and her group at Radboud University Medical Center.","og_url":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/","og_site_name":"LIGHTOX","article_published_time":"2021-02-02T19:59:54+00:00","article_modified_time":"2021-12-07T06:10:49+00:00","og_image":[{"width":1000,"height":707,"url":"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg","type":"image\/jpeg"}],"author":"LIGHTOX TEAM","twitter_card":"summary_large_image","twitter_creator":"@lightox5","twitter_site":"@lightox5","twitter_misc":{"Written by":"LIGHTOX TEAM","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#article","isPartOf":{"@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/"},"author":{"name":"LIGHTOX TEAM","@id":"https:\/\/lightox.co.uk\/#\/schema\/person\/1c4c5240ed66920f7bf1ad0e3cd4034f"},"headline":"Lighting the Way Out of Skin Fibrosis","datePublished":"2021-02-02T19:59:54+00:00","dateModified":"2021-12-07T06:10:49+00:00","mainEntityOfPage":{"@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/"},"wordCount":306,"publisher":{"@id":"https:\/\/lightox.co.uk\/#organization"},"image":{"@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#primaryimage"},"thumbnailUrl":"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg","keywords":["News"],"articleSection":["Collaboration"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/","url":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/","name":"Lighting the Way Out of Skin Fibrosis - LIGHTOX","isPartOf":{"@id":"https:\/\/lightox.co.uk\/#website"},"primaryImageOfPage":{"@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#primaryimage"},"image":{"@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#primaryimage"},"thumbnailUrl":"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg","datePublished":"2021-02-02T19:59:54+00:00","dateModified":"2021-12-07T06:10:49+00:00","description":"LightOx are delighted to announce that we have joined forces with Dr. Marije Koenders and her group at Radboud University Medical Center.","breadcrumb":{"@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#primaryimage","url":"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg","contentUrl":"https:\/\/lightox.co.uk\/wp-content\/uploads\/2021\/02\/APOLLO.jpg","width":1000,"height":707},{"@type":"BreadcrumbList","@id":"https:\/\/lightox.co.uk\/lighting-the-way-out-of-skin-fibrosis\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/lightox.co.uk\/"},{"@type":"ListItem","position":2,"name":"Lighting the Way Out of Skin Fibrosis"}]},{"@type":"WebSite","@id":"https:\/\/lightox.co.uk\/#website","url":"https:\/\/lightox.co.uk\/","name":"LIGHTOX","description":"illuminating therapeutics &amp; research tools","publisher":{"@id":"https:\/\/lightox.co.uk\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/lightox.co.uk\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/lightox.co.uk\/#organization","name":"LightOx Limited","url":"https:\/\/lightox.co.uk\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/lightox.co.uk\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"LightOx Limited"},"image":{"@id":"https:\/\/lightox.co.uk\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/x.com\/lightox5","https:\/\/www.linkedin.com\/company\/lightox-limited\/"]},{"@type":"Person","@id":"https:\/\/lightox.co.uk\/#\/schema\/person\/1c4c5240ed66920f7bf1ad0e3cd4034f","name":"LIGHTOX TEAM","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/lightox.co.uk\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/b2ad47e1a5396b65810aa5710c6ebf4b?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/b2ad47e1a5396b65810aa5710c6ebf4b?s=96&d=mm&r=g","caption":"LIGHTOX TEAM"}}]}},"_links":{"self":[{"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/posts\/2555"}],"collection":[{"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/comments?post=2555"}],"version-history":[{"count":14,"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/posts\/2555\/revisions"}],"predecessor-version":[{"id":2965,"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/posts\/2555\/revisions\/2965"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/media\/2562"}],"wp:attachment":[{"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/media?parent=2555"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/categories?post=2555"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lightox.co.uk\/wp-json\/wp\/v2\/tags?post=2555"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}