“Ultimately, if even one person benefitted from technology developed by LightOx, this would fulfil a lifelong ambition of mine.”
What’s your name and job title?
Dr. David Chisholm – Chemistry Team Leader
How long have you been at LightOx?
Since 2018
Can you share a bit about your previous experience in the health and life sciences industry?
I previously worked as a postdoctoral research associate for Durham University & Aberdeen University, developing novel bioactive compounds for the treatment of neurodegenerative diseases.
What are your particular areas of interest and expertise?
I am an expert in the design and synthesis of bioactive molecules for therapeutic applications. I find the way that molecules can be built up from simple atoms into shapes and structures that respond to external stimuli to be absolutely fascinating, and have built expertise in light-activated chemistry, protein-drug interactions and medicinal chemistry in order to better understand how and why molecules behave in the way they do.
At LightOx, I have relished the challenge of using my fundamental scientific knowledge to design novel technologies and now enjoy developing these ideas into products that create value for the company and have the potential to change the lives of people suffering from challenging illnesses.
What role do you play in the development of LightOx’s new therapies for oral cancer and wound care or in supporting the LightOx business?
I run our Chemistry Team, where I have the pleasure of working with two fantastic chemists, Alba and Eva, developing LightOx’s light-activated chemical technology. This involves coordinating the R&D activities of the team, designing new IP and projects, and pitching in with technical work. I also work closely with the rest of our scientific team to progress our oral cancer and wound care programmes through critical stages of development.
What do you like the most, or find the most interesting about your role?
I am lucky to work in a role that has tremendous variety. One day could involve developing R&D plans, talking to NHS clinicians, carrying out market research, managing IP protection, and carrying out a chemical reaction; whereas the next could be completely different.
I enjoy developing new technology, but also being able to talk to potential end-users and many other parties about what LightOx are doing. Each day is different, and challenging – I’m never bored! Finally, I enjoy being in a business with a supportive, friendly team who are a pleasure to work with.
What does a typical working day at LightOx look like for you?
A typical day involves arriving by cycle/train to our premises in Newcastle, checking in with the rest of the team on the chemistry work and then updating the next few day’s R&D activities. I typically have meetings around an aspect of our oral cancer drug development programme and have lately been working a lot on our wound care product plans. Finally, I may get a chance to get in the laboratory and work on developing our novel chemical technology.
What are your hopes or ambitions for the projects you’re working on?
It would be hugely gratifying to see our technology reach the market and provide new, better options for clinicians. Ultimately, if even one person benefitted from technology developed by LightOx, this would fulfil a lifelong ambition of mine.
When you are not at work how do you like to unwind?
I get most out of life when I am doing things! I love to design and construct my own furniture, play music (I used to teach the guitar, and play the piano), play board games, hike, exercise (cycling, swimming, gym), and try to learn how I can help the environment. I have recently started to brew kombucha and bake more bread, and am currently training with my wife, Hannah, to compete in the national jigsaw puzzle championships.
Who are the 4 guests dead or alive you would invite to your dinner party?
Sir David Attenborough, Boudica, Amelia Earhart and Michael Schumacher.
Finally, in another life what would have been your dream job?
I would be an environmental conservationist, or a carpenter.
